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Attention to the MPV marker is simple and profitable with immediate applicability in daily clinical practice. Compared to the group of MPV ≤ 11.4 fl, patients with MPV > 11.4 fl had increased mortality (log-rank test = 40.35, HR = 8.723, P  11.4 fl is a more useful marker for predicting in-hospital mortality among critically ill patients receiving IMV, especially in female patients.

ResultsĪ total of 274 patients were enrolled in the study, and 42 patients (15.3%) died in hospital. Kaplan–Meier cumulative incidence curve was employed to observe the incidence of in-hospital mortality. Univariate and multivariate Cox regression analysis were conducted to analyze the value of MPV for predicting in-hospital mortality. The receiver operating characteristics curve was used to evaluate the predictive ability of MPV for in-hospital mortality. The patients were divided into two groups by MPV cutoff value. MethodsĪ retrospective observational study including patients receiving IMV was conducted from January, 2014 to January, 2019. Although mean platelet volume (MPV) has been reported to be associated with poor prognosis of various critical illness, the relationship between MPV and in-hospital mortality among patients undergoing invasive mechanical ventilation (IMV) is unclear.